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Data on the impact of OSA on the incidence of hypertension are somewhat conflicting. Sleep-disordered breathing in patients with symptomatic heart failure: A contemporary study of prevalence in and characteristics of patients. Predisposition Predisposing factors for OSA include older age, male sex, smoking, use of muscle relaxants, and endocrine disorders such as hypothyroidism and acromegaly, the most important factor, however, being obesity. Patients with known OSA had shorter hospital stays and did not have the significant differences in one year mortality that was seen with high versus low risk by screening criteria. Gender Although clinic-based studies had previously reported a significant gender gap in the prevalence of OSA, more recent large population-based studies have demonstrated that the prevalence of OSA is only 1. The strongest evidence for adverse cardiovascular events associated with OSA seems to be linked to those with severe disease, whereas the data for the link in mild-moderate patients is less clear.
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