Testing sperm chromatin



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Thermal denaturation of DNA in situ as studied by acridine orange staining and automated cytofluorometry. Fertil Steril 6 This article has been cited by other articles in PMC. Consequently, there was a better recruitment of good-quality oocytes with an intact repair mechanism after they were fertilized by DNA-defective sperm 4 , Fertil Steril ; 73 Hum Reprod 27 1 —7.
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Sperm chromatin structure assay (SCSA): a tool in diagnosis and treatment of infertility


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SCSA Diagnostics: SCSA Test


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Sperm Chromatin Structure Assay (SCSA)

Testing for sperm DNA fragmentation is typically performed at an outside laboratory using a semen sample obtained through ejaculation. Data from these four sperm DNA fragmentation tests plus the light microscope acridine orange test AOT are correlated to various degrees. Very few laboratories have access to such equipment.
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