Effects of progesterone sperm receptor function

Huang, L. Progesterone also modulates sperm function by stimulating a trypsin-like proteolytic activity, the biosynthesis of polyamine putrescine and spermidine , phospholipase A2 activity and protein tyrosine kinase activity in the sperm cell. It was first prescribed in Molecular Endocrinology. Main articles: Progesterone medication , Pharmacodynamics of progesterone , and Pharmacokinetics of progesterone. Nongenomic activation of spermatozoa by steroid hormones: facts and fictions.

Aldo E. However, not all the biological effects of progesterone are mediated by an increase of intracellular calcium. The physiological relevance of these effects has been shown using female genital tract fluids which modulate sperm function according to their progesterone content.